Endometriosis is a common condition where the lining of the uterus grows in other locations, such as the ovaries and the intestines. This disease is extremely painful and often associated with infertility. Despite the high prevalence of the disease (an estimated 10% of women deal with endometriosis during their reproductive years), this condition remains challenging to diagnose and treat. As a result, most treatments for the endometriosis are not curative and have a high number of associated side-effects. Unfortunately, very little is known about the disease at the molecular level, partially due to the lack of suitable experimental models needed to study the disease.
This is where research in bioengineering plays a roll. To provide some insight into this field, we checked in with one of our 2018/2019 WiRe fellows, Dr. Anna Stejskalová, whose research at the University of Münster focused on designing a 3D model of early endometrial lesions.